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Platform for translational research
Data-Driven, Novel Insights, Reliable Results
 

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Identify disease markers and targets based on a vast range of biological criteria
 

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Understand the single-cell expression profile of a target with a single click
 

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Identify cancer targets based on expression profile in healthy and tumor tissues
 

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Multi-criteria target ranking including disease association, tissue expression, PPIs and clinical stage
 

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Do gene set enrichment analysis against a unique collection of multi omics databases
 

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Assess target expression in cell lines to plan your in-vitro experiments
 

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Proven, real-world results

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We have one of the strongest track records in data-driven translational research as our platform and services have contributed to approved drugs and active clinical trials in oncology, Sjogren's disease, Ulcerative Colitis, NASH and epilepsy with 5 different biopharma clients.
 

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Your daily companion for data-driven translational research

The Euretos platform seamlessly integrates a large collection of literature, patents and experimental and clinical & real-world patient data in a vast biological knowledge graph. A broad suite of applications, predictive algorithms and workflows enable researchers to understand disease mechanisms, discover new drug targets and assess pharmacological pathways.

Empowering researchers

The Euretos platform empowers researchers to take a data-driven approach to translational research without needing bioinformatics skills or data science expertise. Ready-to-use applications and workflows enable users to do efficient and effective desk research, experiment design and observation analysis

Novel insights from knowledge graph connections and predictive scores
Reliable interpretation of real-world observations and experimental results
Data-driven research without needing bioinformatics or data science skills
Well-informed design of lab experiments and clinical trials

Novel, AI-predicted gene-disease associations

Euretos has created machine learning models that leverage the biological networks of a target that are stored in our biological knowledge graph such as co-expression, protein-protein interactions and pathways. Our models assess all diseases that are associated through these networks and calculate a gene-disease score which quantifies a gene’s association with the disease, even when there is no direct evidence.

 
tevalogo
"I find the Euretos platform to be valuable in what it offers in terms of advanced AI capabilities and analytics of smart scouting and literature searches to probe relevant targets, indications, and therapeutics. The professional support and dedicated mentoring from experienced bioinformatics professionals that Euretos offers greatly enhances our ability to take advantage of all the capabilities of the platform, and extract meaningful insights for our day-to-day mission of bringing innovation into Teva."
 
Dr. Dana Bar-On - Sr. Director, Head of Academic Affairs and Networks, Specialty R&D, Teva  Pharmaceuticals 
 

Selected functions & workflows

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Disease Targets & Markers

Identify disease markers and targets based on a vast range of biological criteria 

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Single-Cell Expression

Understand the single-cell expression profile of a target within healthy and tumor tissues

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Tumor vs Tissue Expression

Identify cancer targets based on differential expression in healthy versus tumor tissues

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Target Ranking

Multi-criteria target ranking (disease associations, expression, PPIs, clinical stage)

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Target Evaluation

Do a 360 degree biological, functional and commercial evaluation of a target

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Cell-Line Selection

Assess target expression in cell lines to design and plan your in-vitro experiments

Euretos Platform
Application Area

Desk research and scientific writing

The Euretos platform streamlines desk research and scientific writing by integrating literature, patents, and real-world data into a comprehensive biological knowledge graph. Its user-friendly applications enable efficient exploration of existing knowledge and the discovery of new insights, boosting the quality and productivity of research efforts.
  • Interactive systematic review workflow
  • Explore (indirect) knowledge graph connections 
  • Enriched publications (e.g. find similar publications)
Euretos Platform
Application Area

Target Assessment & In-licensing

The Euretos platform enables a data-driven approach to target assessment and in-licensing for pharma. The applications and workflows support informed decision-making and market potential analysis, leveraging a comprehensive blend of literature, patents, and real-world data insights.
  • Comprehensive '360 dagree' target assessment page
  • Detailed expression data (bulk rna, single-cell rna, protein, cell line)
  • Comprehensive market assessment (clinical trials, patents, drug approvals)

 
tevalogo
""We find that the Euretos group was very easy to work and communicate with. The professional staff at Euretos did a great job extending their platform and capabilities to our advantage. Euretos helped us to extract meaningful information from a highly complex data domain, that we could build on internally."
 
Dr. Henriette Husum Bak-Jensen - Project Manager, Projects &Portfolio department, H. Lundbeck A/S;
 
Euretos Platform
Application Area

Target Discovery in disease 

The Euretos platform powers target discovery by combining its biological knowledge graph with predictive AI models to provide insight into complex disease mechanisms and suggest potential novel targets. Focused applications and workflows facilitate the exploration of key aspects such as disease pathways, target expression, multi-omics interactions to assess target suitability.
  • Unique predictions of potential gene-disease associations
  • Multiple workflows for multi-criteria target ranking and assessment
  • Target expression in cell lines and in-vivo models to plan experiments
Euretos Platform
Application Area

Target Discovery in cancer

The Euretos platform advances cancer target discovery by analyzing tumor-specific gene expression, protein interactions, and genetic mutations. It supports comparative analysis of cancerous versus normal tissue profiles and understanding the dynamics of oncogenic pathways. This enables the development of precise, targeted cancer therapies.
  • Multiple workflows to assess  expression in tumor vs healthy tissue
  • Single-cell study viewer to explore published single cell RNAseq data 
  • Target expression in cell lines and in-vivo models to plan experiments
Client review

Target Discovery

"We worked with Euretos to leverage their AI capabilities with the aim of finding new targets in two different indications. It was a real pleasure to work with them and the whole process was characterized by transparency, their willingness to listen to our needs and suggestions, and swift responses and data delivery. In addition, we found their platform very useful for getting an overview of the different targets and for general queries."

Tau Benned-Jensen
Senior Research Scientist, H. Lundbeck A/S
Client review

Indication selection

“In this project, we evaluated you against our internal investigations and the results of one other external provider. What really sets you apart is how you combine a fundamentally biological and data-driven approach. The breadth of the indications you assess and the depth of your analysis sets you apart and is a clear value add to our internal capabilities.”

Large European Pharma
Global Head
Client review

Target Assessment

"I find the Euretos platform to be valuable in what it offers in terms of advanced AI capabilities and analytics of smart scouting and literature searches to probe relevant targets, indications, and therapeutics. The professional support and dedicated mentoring from experienced bioinformatics professionals that Euretos offers greatly enhances our ability to take advantage of all the capabilities of the platform, and extract meaningful insights for our day-to-day mission of bringing innovation into Teva."

Dr. Dana Bar-On
Sr. Director, Head of Academic Affairs and Networks, Specialty R&D, Teva Pharmaceuticals
Client review

Target Discovery

"We have been working with Euretos for many years now. They provide us with unique tools that we use as an integral part of our target discovery and validation. Using the Euretos AI platform is a mandatory input to our target discovery meetings."

Large European Biotech
Director Target Discovery
Client review

Indication Selection

"We find that the Euretos group was very easy to work and communicate with. The professional staff at Euretos did a great job extending their platform and capabilities to our advantage. Euretos helped us to extract meaningful information from a highly complex data domain, that we could build on internally."

Henriette Husum Bak-Jensen
Project Manager, Projects & Portfolio department, H. Lundbeck A/S
Client review

Target Assessment

"We are fascinated by the suggested hypothesis. It was great that even very small expressional changes were captured and a hypothesis was generated. The interpretation was also convincing and consistent. Also, the team is well engaged, and had a very good understanding in the background of the project and our research question"

Large Japanese Pharma
Principal Scientist

Data-driven disease insights

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